Lipase

What is Lipase?

Lipase is a digestive enzyme that plays a crucial role in breaking down dietary fats into smaller molecules, primarily fatty acids and glycerol. Produced mainly by the pancreas and secreted into the small intestine, lipase catalyzes the hydrolysis of triglycerides, facilitating their absorption and utilization by the body. This enzyme operates optimally in the presence of bile salts, which emulsify fats and enhance the enzyme's effectiveness.

What causes Lipase deficiency?

Lipase deficiency can result from conditions like pancreatic insufficiency, chronic pancreatitis, cystic fibrosis, and some genetic disorders that reduce enzyme production. Surgery involving the pancreas or bile duct obstructions, as well as digestive disorders like celiac disease, can also affect lipase levels. Symptoms include bloating, gas, diarrhea, and cramping, especially after eating fatty foods. Stools may be pale, foul-smelling, and float due to undigested fat. The body may struggle to absorb fats and fat-soluble vitamins, leading to weight loss, vision issues, weakened immunity, bone weakness, poor skin health, fatigue, and low energy levels.

What can I do about it?

To manage lipase deficiency, consider taking pancreatic enzyme replacement therapy (PERT) under the guidance of a healthcare provider. This involves consuming enzyme supplements that help in digesting fats and improving nutrient absorption. Dietary adjustments can also help; focus on a low-fat diet to reduce the strain on digestion and option for easily digestible foods.