Protease

What is Protease?

Protease is a type of enzyme that breaks down proteins into smaller peptides and amino acids, facilitating their absorption and utilization by the body. These enzymes are produced in various parts of the digestive system, including the stomach (pepsin), pancreas (trypsin and chymotrypsin), and small intestine.They also help in cell regulation, immune function, and the recycling of proteins within the body.

Why causes a Protease deficiency?

Protease deficiency can result from conditions like pancreatic insufficiency, chronic pancreatitis, cystic fibrosis, pancreatic cancer, or genetic disorders such as Shwachman-Diamond syndrome. Poor diet and gut health issues, like leaky gut or dysbiosis, can worsen the deficiency. Symptoms include bloating, gas, and stomach pain after protein-rich meals, as well as fatigue, muscle weakness, and brittle hair from reduced amino acid absorption. Low protease levels may increase food sensitivities, infection risk, and gut inflammation, potentially worsening IBS symptoms.

What can I do about it?

To address a protease deficiency, consider incorporating enzyme-rich foods into your diet, such as pineapple (which contains bromelain) and papaya (which contains papain). Over-the-counter enzyme supplements, particularly those containing proteases like bromelain and papain, can help improve protein digestion.