S-Adenosyl-L-Methionine (SAMe)

What is S-Adenosyl-L-Methionine (SAMe)?

S-Adenosyl-L-Methionine (SAMe) is a naturally occurring compound in the body that plays a role in methylation processes, which are essential for neurotransmitter production, liver function, and joint health. It is synthesized from methionine, an amino acid found in various protein-rich foods like meat, fish, and eggs.

Why do I have an intolerance?

SAMe intolerance may arise if your body has difficulty processing or regulating methylation pathways. This can lead to an overproduction or underproduction of certain byproducts, causing adverse reactions such as mood changes, digestive issues, or discomfort after consuming SAMe-rich foods or supplements.

What can I do about it?

To manage SAMe intolerance, consider reducing your intake of methionine-rich foods or SAMe supplements. You may also benefit from balancing methylation by including foods high in folate, vitamin B12, and other B vitamins, which help regulate this process.